Papilloma viruses affect a wide variety of animals. They cause tumors that erupt from DNA mutations in humans, monkeys, deer, horses, cattle, dogs, birds, and rabbits. The Los Alamos National Laboratory in the United States maintains a database of papilloma virus genomic sequences and a phylogenic tree, both of which are available at HPV Sequence Database.
Human papilloma viruses (HPVs) produce epithelial tumors of the skin and mucous membranes. More than 100 HPV types have been detected, and the genomes of more than 80 have been completely sequenced. The current classification system, which is based on similarities in their genomic sequences, generally correlates with the 3 categories used to describe HPV clinically: anogenital and/or mucosal, non-genital cutaneous, and epidermodysplasia verruciformis (EV).
The mucosal HPV infections are classified further as latent (asymptomatic), subclinical, or clinical. Clinical lesions are grossly apparent, whereas latent infections are detected only with tests for viral DNA. Subclinical lesions are identified by application of 3-5% acetic acid and inspection under magnification. Most HPV infections are latent; clinically apparent infections usually result in warts rather than malignancies.
HPV types 6 and 11 are typically labeled as low risk because infection with these types has low oncogenic potential and usually results in the formation of condylomata and low-grade precancerous lesions. HPV types 16 and 18 have emerged as the high-risk types of HPV because they are responsible for most high-grade intraepithelial lesions that may progress to carcinomas, particularly those in the anogenital and/or mucosal category.
HPV infection alone does not cause malignant transformation of infected tissue. Cofactors, such as tobacco use, ultraviolet radiation, pregnancy, folate deficiency, and immune suppression have been implicated in this process.
HPV infection is the most common sexually transmitted infection in the United States. The number of patients identified with HPV disease has increased markedly during the past 20 years because of heightened awareness of the various manifestations of HPV disease and because of increased use of HPV DNA testing.
Patients receiving immunosuppressive drugs and patients with defects in cell-mediated immunity, including those infected with the human immunodeficiency virus (HIV), are especially susceptible to developing HPV infections.
In the United States, 2.5 million women are estimated to have an annual cytological diagnosis of a low-grade cervical cancer precursor. HPV infection causes virtually all cases of cervical cancer. No deaths due to cervical cancer have been documented in women younger than 20 years. The United States National Cancer Institute publishes data on prevalence of worldwide cervical cancer via their online database.
The incidence of cervical cancer has decreased dramatically during the last century because of implementation of the Papanicolaou test (Pap Test, or Pap smear) beginning in the 1930s and 1940s. However, from 1990-2001, the annual number of estimated new invasive cervical cancers remained relatively constant, ie, 13,500 and 12,900, respectively.
Anogenital warts, or condylomata acuminata, are the most commonly diagnosed viral sexually transmitted disease (STD) in the United States and the United Kingdom. The annual incidence is estimated between 500,000 and 1 million cases. From 1966-1986, the incidence of genital warts increased 5-fold.
Most doctors use cauterization or freezing as a first option to cure genital warts. Unfortunately, success achieved with this method is often temporary and the warts soon reappear. For genital warts, cures may involve having to surgically excise or burn them off. After surgical intervention or chemical acids are used, one can expect a scar in that area.
HPVCurative is a new, highly effective and potent way to cure genital warts. It is valued for its role in the realm of genital warts cures, and has provided total clearance of the infection time after time. It contains certified organic medicinal plant extracts and antiviral essential oils, which have demonstrated the ability to act as an HPV cure in laboratory tests.
Alkaloids exhibiting a broad spectrum of antiviral activity have been identified in a select few herbal extracts, which have been blended into all of our HPV cures. These antiviral alkaloids can penetrate into human tissue, and are known to be highly effective in genital warts cures. Applying antimicrobial herbal substances to the skin to treat specific ailments is a time-honored practice with proven effectiveness.
CURED remains one of the only companies with the advanced know-how required to effectively concentrate these naturally occurring anti-tumor compounds in a HPV cure. HPVCurative is truly a powerful and highly developed way to cure genital warts. To learn more, please go to http://www.bcured.net.
Originally posted here: Elementary Knowledge of HPV
